钨丝微电极阵列的简易制备方法
An easy-to-prepare method for fabrication of tungsten microelectrode array
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摘要: 本文提出了一种简易、低成本的钨丝微电极阵列制作工艺和方法。该方法采用MEMS工艺制作的玻璃模具实现钨丝阵列的精密有序排列,同时,在钨丝电极表面涂覆一层光敏性的聚酰亚胺作为绝缘层,结合“双面光刻”技术和电化学腐蚀技术实现电极位点大小和电极丝几何尺寸的精确控制。最后,通过注模、光刻制作SU-8固定座体完成钨丝微电极阵列的组装固定。整个制作工艺简单快速,且玻璃模具可重复使用,大大降低了制作成本。此外,本文还测试和评价了所制作微电极的表面形貌、电学性能以及生物相容性。Abstract: This paper provides a detailed process flow for fabricating an easy-to-prepare,inexpensive array of tungsten microelectrodes.Firstly,a MEMS-based glass mold was used to align the tungsten probes which had been coated with a layer of photosensitive polyimide.A combination of double-side photolithography and electrochemical etch was then performed to precisely define the length of probes and the shape of probe tips.Finally a SU-8 holder was fabricated with molding and photolithography to fix the array of tungsten probes.The whole process is simple and fast,which involve a reusable glass mold,so it greatly reduces the time and cost of fabrication of neural probes.Results are discussed on the geometrical,electrical properties and biocompatibility of the tungsten microelectrode array.
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