Abstract: The deformation of micro-pump in virtual environment is discussed in this paper. The deformation of micro-pump involves the deformation of micro-valve operation under pressure and the deformation of dual-metal driving devices, the conclusion that they all are scale deformation has been obtained; the stratery that the deformation of complex objects can be implemented with kinematics of a group of simple objects are put forward, the corresponding mathematical descriptions are given; finally, the algorithm of implementing the deformation of micro-pump is given.