Abstract: La_0.5-xPr_xBa_0.5CoO₃ Compounds were prepared by the solid state reaction. Magnetic and transport properties of the materials with different Pr content were studied systematically. The results show that substitution of Pr does not change the itinerant properties of t he 3d electrons of Co. The molecular moment of the materials decreases with Pr content increasing monotonically, because the spin state of Co ions in the samples transits from intermediate to low spin state gradually. The Curie temperature of the materials decreases with Pr content increasing, due to the size effect of the rear -earth ions.The electric resistance measurements show that, for all the doped materials in tested temperature range, below Curie temperature, the conductive mechanism of the materials belongs to the thermal diffusion; and over Curie temperature, it becomes variable-range hopping mode.